IARC MONOGRAPHS VOLUME 24

itis, B.C. & Bartlett, C.D. (1975
Nature, 254, 532-533 -

*
ie

) Substitution at an emino nitrogen.
© Group, Vol. 1, New York, Interscie

i
In: Patai, S., ed, F2M,

lis, B.C. & Butler, A.R, (1968
nce, pp. 365.320 .

The Chemistry of the Amin

n, W.C. & Fong, Y.Y. (1977) Ascorbic acid
pyrine and nitrite in the tat. Int. J, Cancer,

prevents liver tumour
20, 268-270

m, H., Loewe, L. & Bunton,

C.A. (1960) Oxidation of ascorble acid by nitrous actd,!
VI. Review and discussion of i

the results (Ger.). Hely. chim, Acta, 43, 320-333:

as

‘ies, R., Dennis, M.J., Massey, R.C. & McWeeny, D.J. (1978) Some effects of phenol.
and thiol-nitrosation reactions on N-nitrosamine formation, tn: Walker, E.A.,

Castegnaro, M., Griciute, L. & Lyle, R.E., eds, Environmental sspects of N-Nitroso
Compounds (IARC Scientific Publications No. 19}, Lyon, Intemational Agency for,

Research on Cancer, pp. 183-197

Gare

"Gare

genic nitrosamines In tobacco, .

iekrey, H. & Preussmann, R. (1962) Formation of carcino:
smoke (Ger.}. Naturwissenschafften, 49, 498-499

R. {1964) Selective production’ ~
rosopiperazina, nitroso-

ackrey, H., !vankovic, S., Mennel, H.D. & Preussmann,
of carcinomas of the nasal cavity in rats with N.N-dinit
piperidine, nitrosomorpholine, methylallyl-, :
(Ger.). 2 Krebsfotsch., 66, 138-150
uckrey, H., Preussmann, R., Ivankovic, S, & Schmahl, D. (1967) Organotropic carcing; Sree
genic action of 65 different N-nitroso compounds in BD rats (Ger). Z Krebsforsch,
69, 103-201

ienbrand, G. & Preussmann, RA, (1975) Nitrosation of phenacetin, Formatic:
nitroso-2-nitro-4-ethoxyacetanilide a5 an unstable product of the nitrosation j
aqueous-acidic solution, Arzneimittel.-forsch., 28, 1472-1475

enbrand, G., Preussmann, R, & Schmihl, D.
- ephedrine in rats. Cancer Lett., 5, 103-10:

(1978) Carcinogenicity of N-nitroso-
6

senbrand, G., Spiegethalder, B., Kann, J., Klein, R. & Preussmann, R. (1979) Carcino-
genic N-nitrosodimethylamine a a contamination in drugs containing ‘-dirnethyt. i
amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one . famidopyrine, uminophenazone). ein

Arzneimittel.-forsch., 29, 867-869

° : . . . ses t
} Possible cocarcinogenic effects of coffee constituents,’ Elesp ur, RAK. & Lijinsky,
if ¢olf following activati
a

_ iFridman, A.L, Mukhametshin,

ia, H,

-Garcla, H.; Keofer, L., Lijinsky,

dimethyl- and methylvinytnitrosamines Oreenblatt, M. & Mirvish, 8. (1972

N-NITROSATABLE DRUGS

W. (1976) Mutagenicity of cyclic Nitrosamines in
on with rat fiver microsomes.

(20) 30
Escherichia -
Cancer Res., 36, 4099-4101

THY. & Tannenbaum, S.R. (1973
nitrosomarpholine from morph
other anions, J. Agric. Food C, em.,. 21, 237-240

Methapyrilene in Fats and the.

Nitrite in Rats as of Apri! 30, 1979, F rederick, MD

{1971} Advances in the
4-50

F.M. & Novikoy, SS,

chemistry of
Russ. chem, Rev., 40,3 ‘

aliphatic N-nitrosamines.

fa, H. & Lijinsky, W.
zZ, Krebsforsch, 77,2

(1972} Tumorigenicity of five cyclic nitrosamines in MRC rats.
57-261 ;
> & Lijinsky, W. (1973

ct in feeding of nitrosamino
acids and of low doses of

”. Krebsforsch., 79, 141-144

W. & Wenyon, C.E.M,
sop)

(1970) Carcin

ogenicity of nitroso-
perazine in rats, Z. Krebsforsch., .

thlomorpholine and T-nitro: 74,179-184

) Dose-response Studies with concurrent administration
of Piperazine and sodium nitrite to strain A mice. y, natl Cancer inst, 49, 119-124
ish, S. & So, B.T. (1971) Ni
nt administration of so
cer inst, 46, 1029-1 034

nblatt, M., Miry trosamine studies:

dium nitrite and s

induction of lung

econdary amines in
Swiss mice, J. nat} Can

ger, J.H., Glass, A.M, & Mantel,

. Carcinogens.. Report on the activity of derivatives of

aromatic amines, nitrosamines, quinolines, nitroalkanes, amides, epoxides, aziridines,
and purine antimetabolites. J, nat! Cancer Inst., 47, 985-1036 :

, GE. (1963) The rea

ction cf tertiery amines with nitrous acid. J. chem, Educ., 40,
181-184 :