By Lawrence E. Lamb, M.D.

DEAR DR. LAMB ~I think it.
would be of interest La many’
of us if you would explain just
what happens to a person
when he has a hangover,

.What causes those awful
eye pains and headache? Is it
the alcohol’s reaction on

. veins“ or muscles. or both?
Some people's hands shake so
bad they can’t hald'a cup of
coffee?- Why? How. about
being thirsty all the. ‘time?.
What organs are affected to
-eause both, vomiting and
diarrhea? Are-all argans of:
the body affecled by alcohol?

DEAR READER — Alcohol
is a cellular: toxin. It -seeps

. dir ectly into any cell it comes ,
in contael with. {i coagulates
protein, and’ you: know. that
our cells contain lots af pro-
tein vital to- their. function, .
Our food and many other
substances.. are .Lransported
into the cells through ‘com-
-plex chemical processes, but
alcohol voes right through. -

In- the bloodstream ‘it,
causes the red blodd’ cells. to
tend to stick together. In this
way they can clump and plug
up smallarteries. This in turn ,

‘interferes with ‘getting: ont ‘with clumped red blood celts,

-ypen to vital cells.
a The: headach
-eyeache, which'can be a part
-ol a hangover, are ‘caused by |
the overdilatation of the ar-
Lteries in the brain region and

and the.

varound “the “skull:’ These ar-:°

*leries -have:.small “nerve
-fibers, in: theiré walls. ‘Pho ~
Foverstretehed arteries stimu-
Hate. the tiny nerves too much

. ‘and set up: the ‘pain pattern.
Coffee contains cafteine,- and ..

2 this drug causes the arler ies

“lo: consiriel- Bythis ‘action “+ *

cotfce sometimes Helps to

relieve“ the hangover
headache,
The | problem with using

coffee is thal the caffeine also ~

slimulates the stomach to
pour oula lot of acid pepsin

What is a hangover?

juice. This is hard-on a

stomach already irritated by -

alcohol. The alcohal tends to
dissolve away the protective
mucuscoating over the lining
of the stemach, and the cells

are: exposed directly to the -
action of aleohol. This-leads ~

to inflammation of the-
stomach, pain, sometimes,

nausea and vomiting. A’ simi: :
-lar.action:is irritalin

to.the
inteslines that. disturbs their.

function which can lead: to oe

diar rhea.

Alcohol alsa causés the kid
neys to. eliminate a, lot of
-waler. This is brought about

_by_a-complex endocrine

reflex mechanism. The end

“result is Unit the body loses a ,-
lot. of water. that iL needs. :-- :
That causes the thirst afler. i927.
lhe ‘drinking episode. The. .
‘thirst stimulates you {0 —
replace the- needed body

waler, .

“With: “gach alcoholic
episode some brain cells are
damaged, possibly from the
alcohol action. and possibly

: indirectly because of plug~

ging--up, the small arteries

decreasing oxygen delivery.
In any case the person who
“drinks a tot loses the normal

Vabilily to learn, and after

death the damaged -areas of
the brain can be observed.
The alcohol's bad effectson

“the nerve cells. affect’ coor-

‘dination, and the changes in
body ‘cheinisiry affect the

“ musele-ncive ‘smicoth coor-

dination. As a result, shakes
occur. :

in ‘fenoral, ‘aleohol does

-~ affect the whole body. I can’t
- think of anything good il does

except act as a social lubri-
cant and’ a sedative — even
the -later is not always the
ase.

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AR ANN LANDERS:
arkapa you will remember me
because I produced an unex-

“pected avalanche of mail for

‘ou. (and: myself) when I
eported some’ scientific . fln-
ings which took marijuana out
{ the. “harmless” class and
termed it “a present danger and
‘possibly more destructive to

“future generations than we now

reallze.””
My name is Hardin B. Jones. 1

-zam- a Professor ‘of Medical

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The Minister af tteatth. ihe . it ~
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amended effective May 1, 1974,

to increase the maximum daily.

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maximum rate is now $75 per
day. Mr. Cocke emphasized that

the change will be particularly: "

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Physics-and Physiology at the
University: of California at
Berkeley. 1 serve also as the

Assistant Director of Donner —

Laboratory. .

Here is additfonal. in-
formation resulting from
recently concluded studies, I
hope you will “share it with your
readers. Professor Stenchever,
University of Ulah Medical
School, has found that most of
the psychedelic drugs he -has
tested, including LSD, do NOT
cause measurable chromosome
damage, but marijuana . and
hashish DO. Furthermore, the «
effect appears to be of con-
‘siderable consequence.

Moreover, almost as much ©

damage occurs with occasional
use as With daily use.

What worries us -is that
broken chromosomes are
symptoms of severe “damage to

the genes, We can see these —

chromosome breaks .with a
microscope but the genes are
still too small to be seen in
detail,
equipment.

Jn current reports of scientific
studies, animals exposed to
marijuana or hashish produce.a

larger number of deformed ">. =
offspring. Alsa, in. the lower".
social strata of foreign coun- .-

tries where hashish “and
marijuana are.

children. Most. of the affected

newhorns do not survive *:
meager :

because of the. m™
resources of these people.

1 have been informed by.
physicians who see babies born”:
to drug-cullure ‘persons in this -
vountry that-they, (00, 56.8 °

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WEDNESDAY, MAY 15, 1974.

disproportionate number of
malformed infants. The effect
may be the result of smoking
marijuana during pregnancy or
of gene damage in the

- developing embryo.

In his recent baok,
“Marijuana: Deceptive Weed,”
Professor Gabriel Nahas of
Columbia University states that

marijuana definitely damages
the ‘genes. Prof, Nahas is
cersidered a highly respected
eatherity in this field. “

“Tied in with this new scien-

_ tific evidence is the finding

(mentioned inmy original letter’.
to you) that there is now -a-
growing bady of evidence that
marijuana smokers .do have
memory problems. -

In my own work, which is

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have extensive proof that those

who stop using marijuana are, ‘-

amazed when they witness the
return of functions they. didn't
realize they had last.. ans
I hope this: i3 helpful toryou,
Ann. — Hardin B » Sones. .
DEAR DR."

indeed. I am deeply grateful for
your follow-up letter, telling of

the progress made. in resear- -

ching the long-range | effects of
“pot and hash. - yer PA et

i‘fervently. hope’ that: your
letter ‘will, be: noted uby.

* legislators who want to legalize.

marijuana and: thatthe’ pot-
heads out: there will pa:
‘tention. -

we

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> JONES: °
Helpful” is: a’ ‘modest: work, -